We are a clinical-stage biopharmaceutical company committed to developing oral drugs for chronic respiratory diseases, focusing on the high unmet need of COPD patients.
EpiEndo Pharmaceuticals was founded on the knowledge that azithromycin reduces exacerbations of COPD and other respiratory diseases, effects that go beyond its antibacterial properties. However, when used chronically it promotes the development of antimicrobial resistance (AMR), which is one of the greatest global healthcare risks according to the World Healthcare Organisation (WHO).
EpiEndo Pharmaceuticals is developing a non-antibiotic macrolide, glasmacinal (previously known as EP395), which aims to expand the therapeutic options for chronic respiratory diseases beyond inhaled bronchodilators and corticosteroids with an oral treatment for respiratory diseases.
COPD is the third largest cause of death globally, causing irreversible airflow obstruction.
Exacerbations of chronic respiratory diseases are mainly caused by viruses, bacteria and airborne irritants that must overcome several respiratory defence barriers and the adaptive immune system before they are able to cause infection or cause damage.
Glasmacinal has the potential to become a unique and impactful treatment option for COPD patients with its host defense response and anti-inflammatory properties.
Glasmacinal was developed to retain the beneficial properties of macrolides but without exerting antimicrobial activity. It is an oral anti-inflammatory drug that also enhances the host defense response and is expected to be able to be taken long-term without risking the development of antimicrobial resistance.
Treatment of COPD patients with glasmacinal has the potential to be an impactful addition to current therapy via reduced severity, frequency and duration of exacerbations and hospitalisation. EpiEndo is committed to improving the quality of life of COPD patients whilst reducing the high society & economic burden of the disease.
Our new class of oral drugs, known as Barriolides™, have the potential to be first-in-class oral therapies for COPD and other chronic respiratory diseases.
We are committed to sustainability and to minimizing our environmental impact and we are working towards formalizing our ESG policies. We measure ourselves against the United Nations Sustainable Development Goals and have implemented internal goals and policies that align with these goals.
EpiEndo aims to improve the quality of life of people with chronic diseases caused by epithelial dysfunction.
EpiEndo is committed to having an inclusive work culture with a healthy balance between work and private life.
EpiEndo, through its collaborative way of working, will continue to innovate and expand the life-science industry in Iceland.
EpiEndo works towards responsible consumption and production internally and externally.
At EpiEndo, we are dedicated to conducting our business with integrity and upholding the highest ethical standards. Our code of conduct sets the standard for our employees, partners, and suppliers, and outlines our commitment to ethical behavior, compliance with laws and regulations, and respect for the rights and dignity of all individuals. Our code of conduct reflects our values and our commitment to conducting business with the highest level of professionalism and ethical standards.